The Payoff

    Use when matched

    GLP-1 medications

    In the right patient the trial evidence is strong. They are a prescribed, clinically supervised intervention — not a longevity shortcut.

    USE WHEN MATCHEDEvidence: Strong in eligible patientsReviewed by the Beyond23 medical team

    A powerful clinical tool for appropriate metabolic risk — not a universal longevity drug.

    Cost and effort, honestly

    Cost
    High
    Effort
    Medium

    What the evidence supports

    GLP-1–based medications can produce substantial weight loss, improve glycaemic control and reduce cardiovascular events in certain eligible populations.

    Most relevant when

    Obesity, type 2 diabetes or related cardiovascular risk meets clinical treatment criteria.

    Keep in perspective

    Results from high-risk clinical populations should not be generalised to every person seeking longevity. Different medications and doses are not interchangeable.

    Safety

    Requires physician prescribing and follow-up. Gastrointestinal effects are common; gallbladder complications and other contraindications must be considered. Weight loss should be paired with resistance training and adequate nutrition to protect lean tissue.

    Sources

    Your payoff

    See whether this belongs in your plan, what it could realistically change, and where it ranks against your other options.

    • Personal relevance
    • Signals it may improve
    • Priority versus your alternatives
    • Recommended starting point
    • How we would track response

    Requires your health history, labs and available wearable data.

    Educational information, not a diagnosis or prescription. Medication decisions require consultation with a qualified clinician.